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2018 Month : July Volume : 7 Issue : 29 Page : 3270-3274

ASSOCIATION OF THYROID FUNCTION WITH BMI, BODY FAT % AND VISCERAL FAT LEVEL IN HEALTHY EUTHYROID INDIVIDUALS

Yumnam Anjana Devi1, Keisam Reetu Devi2, Avinash Keisam3, Sangeeta Mayanglambam4

1Associate Professor, Department of Physiology, JNIMS, Imphal, Manipur, India.
2Assistant Professor, Department of Physiology, JNIMS, Imphal, Manipur, India.
3Assistant Professor, Department of Community Medicine, JNIMS, Imphal, Manipur, India.
4Demonstrator, Department of Physiology, JNIMS, Imphal, Manipur, India.

References :

1

Haslam DW, James WPT. Obesity. The Lancet 2005;366(9492):1197-209.               

CrossRef | PubMed
2

Roos A, Bakker SJ, Links TP, et al. Thyroid function is associated with components of the metabolic syndrome in euthyroid subjects. Journal of Clinical Endocrinology and Metabolism 2007;92(2):491-6.            

CrossRef | Google Scholar | PubMed
3

De Pergola G, Ciampolillo A, Paolotti S, et al. Free triiodothyronine and thyroid stimulating hormone are directly associated with waist circumference, independently of insulin resistance, metabolic parameters and blood pressure in overweight and obese women. Clinical Endocrinology (Oxf) 2007;67(2):265-9.           

CrossRef | Google Scholar | PubMed
4

Tagliaferri M, Berselli ME, Calo G, et al. Subclinical hypothyroidism in obese patients: relation to resting energy expenditure, serum leptin, body composition and lipid profile. Obese Res 2001;9(3):196-201.                   

CrossRef | Google Scholar | PubMed
5

Kitahara CM, Platz EA, Ladenson PW, et al. Body fatness and markers of thyroid function among U.S. men and women. PLoS One 2012;7(4):e34979.    

CrossRef | Google Scholar | PubMed
6

WHO, Obesity: preventing and managing the global epidemic. Report of a WHO Consultation on Obesity, World Health Organisation, Geneva, Switzerland, 1998.              

7

Al-Musa HM. Impact of obesity on serum levels of thyroid hormones among Euthyroid Saudi Adults. Journal of Thyroid Research 2017;2017:5739806.  

CrossRef | Google Scholar | PubMed
8

Knudsen N, Laurberg P, Rasmussen LB, et al. Small differences in thyroid function may be important for body mass index and the occurrence of obesity in the population. J Clin Endocrinol Metab 2005;90(7):4019-24.              

CrossRef | Google Scholar | PubMed
9

Solanki A, Bansal S, Jindal S, et al. Relationship of serum thyroid stimulating hormone with body mass index in healthy adults. Indian J Endocrinol Metab 2013;17(Suppl 1):S167-9.                  

CrossRef | Google Scholar | PubMed
10

Nyrnes A, Jorde R, Sundsfjord J. Serum TSH is positively associated with BMI. Int J Obes (Lond)  2006;30(1):100-5.              

CrossRef | Google Scholar | PubMed
11

Kumar HK, Yadav RK, Prajapati J, et al. Association between thyroid hormones, insulin resistance and metabolic syndrome. Saudi Med J 2009;30(7):907-11.          

Google Scholar | PubMed
12

Chan JL, Heist K, De Paoli AM, et al. The role of falling leptin levels in the neuroendocrine and metabolic adaptation to short term starvation in healthy men. The Journal of Clinical Investigation 2003;111(9):1409-21.              

CrossRef | Google Scholar | PubMed
13

Auwerx J, Staels B. Leptin. Lancet 1998;351(9104):737-42.               

CrossRef | Google Scholar | PubMed
14

Ortiga-Carvalho TM, Oliveira KJ, Soares BA, et al. The role of leptin in regulation of TSH secretion in fed state: in vivo and in vitro studies. J Endocrinol 2002;174(1):121-5.       

CrossRef | Google Scholar | PubMed
15

Aeberli I, Jung A, Murer SB, et al. During rapid weight loss in obese children, reductions in TSH predict improvements in insulin sensitivity independent of changes in body weight or fat. J Clin Endocrinol Metab 2010;95(12):5412-8.                

CrossRef | Google Scholar | PubMed
16

Menendez C, Baldelli R, Camina JP, et al. TSH stimulates leptin secretion by a direct effect on adipocytes. J Endocrinol 2003;176(1):7-12.            

CrossRef | Google Scholar | PubMed
17

Galofre JC, Pujante P, Abreu C, et al. Relationship between thyroid-stimulating hormone and insulin in euthyroid obese men. Ann Nutr Metab 2008;53(3-4):188-94.       

CrossRef | Google Scholar | PubMed
18

Makepeace AE, Bremner AP, O’Leary P, et al. Significant inverse relationship between serum free T4 concentration and body mass index in euthyroid subjects: differences between smokers and non-smokers. Clin Endocrinol (Oxf) 2008;69(4):648-52.        

CrossRef | Google Scholar | PubMed
19

Manji N, Boelaert K, Sheppard MC, et al. Lack of association between serum TSH or free T4 and body mass index in euthyroid subjects. Clin Endocrinology (Oxf) 2006;64(2):125-8.                      

CrossRef | Google Scholar | PubMed
20

Alevizaki M, Saltiki K, Voidonikola P, et al. Free thyroxine is an independent predictor of subcutaneous fat in euthyroid individuals. Eur J Endocrinol 2009;161(3):459-65.          

CrossRef | Google Scholar | PubMed
21

Kok P, Roelfsema F, Frolich M, et al. Spontaneous diurnal thyrotropin secretion is enhanced in proportion to circulating leptin in obese premenopausal women. J Clin Endocrinol Metab 2005;90(11):6185-91.              

CrossRef | Google Scholar | PubMed
22

Teixeira PF, Cabral MD, Silva NA, et al. Serum leptin in overt and subclinical hypothyroidism: effect of levothyroxine treatment and relationship to menopausal status and body composition. Thyroid 2009;19(5):443-50.               

CrossRef | Google Scholar | PubMed
23

Choi SH, Lee YJ, Park YJ, et al. Retinol binding protein-4 elevation is associated with serum thyroid-stimulating hormone level independently of obesity in elderly subjects with normal glucose tolerance. J Clin Endocrinol Metab 2008;93(6):2313-8.         

CrossRef | Google Scholar | PubMed
24

Pinkney JH, Goodrick SJ, Katz J, et al. Leptin and the pituitary-thyroid axis: a comparative study in lean, obese, hypothyroid and hyperthyroid subjects. Clin Endocrinol (Oxf) 1998;49(5):583-8.                  

CrossRef | Google Scholar | PubMed
25

Ortega E, Pannacciulli N, Bogardus C, et al. Plasma concentrations of free triiodothyronine predict weight change in euthyroid persons. Am J Clin Nutr 2007;85(2):440-5.         

CrossRef | Google Scholar | PubMed
26

Zhang J, Sun H, Chen L, et al. Relationship between serum TSH level with obesity and NAFLD in euthyroid subjects. J Huazhong Univ Sci Technolog Med Sci 2012;32(1):47-52.

CrossRef | Google Scholar | PubMed
27

Mukherjee S, Mukhopadhyay D, Chakraborty P. Relationship between Body Mass Index (BMI), body fat percent and serum TSH level in euthyroid female subjects. International Journal of Science and Research (IJSR) 2015;4(6):1697-700.

28

Mihaly E, Fekete C, Tatro JB, et al. Hypophysiotropic thyrotropin-releasing hormone-synthesizing neurons in the human hypothalamus are innervated by neuropeptide Y, agouti related protein, and alpha- melanocyte-stimulating hormone. J Clin Endocrinol Metab 2000;85(7):2596-603.

CrossRef | Google Scholar | PubMed
29

Sorisky A, Bell A, Gagnon A.TSH receptor in adipose cells. Horm Metab Res 2000;32(11-12):468-74.           

CrossRef | Google Scholar | PubMed
30

Valyasevi RW, Harteneck DA, Dutton CM, et al. Stimulation of adipogenesis, peroxisome proliferator-activated receptor gamma (PPARgamma), and thyrotropin receptor by PPAR gamma agonist in human orbital pre-adipocyte fibroblasts. J Clin Endocrinol Metab 2002;87(5):2352-8.        

CrossRef | Google Scholar | PubMed
31

Betry C, Challan-Belval MA, Bernard A, et al. Increased TSH in obesity: evidence for a BMI independent association with leptin. Diabetes Metab 2015;41(3):248-51

CrossRef | Google Scholar | PubMed
32

Bandurskha-Stankiewicz E. Thyroid hormone-obesity and metabolic syndrome. Thyroid Research 2013;6(Suppl 2):A5.               

PubMed
33

Nannipieri M, Cecchetti F, Anselmino M, et al. Expression of thyrotropin and thyroid hormone receptors in adipose tissue of patients with morbid obesity and/or type 2 diabetes: effects of weight loss. Int J Obes (Lond) 2009;33(9):1001-6.          

CrossRef | Google Scholar | PubMed
34

Goodpaster BH, Krishnaswami R, Harris TB, et al. Obesity, regional body fat distribution and the metabolic syndrome in older men and women. Arch Intern Med 2005;165(7):777-83.                              

CrossRef | Google Scholar | PubMed
35

Westerink J, Van der Graaf Y, Faber DR, et al. The relation between thyroid-stimulating hormone and measures of adiposity in patients with manifest vascular disease. Eur J Clin Invest 2011;41(2):159-66.              

CrossRef | Google Scholar | PubMed
36

Muscogiuri G, Sorice GP, Mezza T, et al. High-Normal TSH values in obesity: Is it insulin resistance or adipose tissue’s guilt? Obesity (Silver Spring) 2013;21(1):101-6. 

CrossRef | Google Scholar | PubMed