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2020 Month : March Volume : 9 Issue : 9 Page : 603-607

Study of Morphological Patterns of Leprosy in a Rural Setup.

Sweety Haribhau Gulhane1, Keshao Madhukar Hiwale2, Arvind Shridhar Bhake3, Sunita Vagha4, Samarth Shukla5

Corresponding Author:
Dr. Sweety Haribhau Gulhane,
Department of Pathology,
Jawaharlal Nehru Medical College,
Archarya Vinoba Bhave Rural Hospital,
Sawangi (Meghe) Wardha,
Maharashtra, India.
E-mail: sweetygulhane@gmail.com

ABSTRACT

BACKGROUND

Leprosy is a chronic disease of ancient world and is still afflicting patients in many parts of world mainly Asia and Africa. Leprosy is one of the most dreaded diseases of humankind. We wanted to study the various microscopic patterns and subtypes of Leprosy. We also wanted to study the Bacterial Index in the region of Sawangi, Meghe.

METHODS

80 skin biopsies after adequate fixation in 10% of formalin, were routinely processed and were stained with H and E, Fite-Faraco stain and Modified Rapid Acid-Fast Bacilli (MRAFB staining) method, were studied microscopically and bacterial index was calculated.

RESULTS

A total of 80 skin biopsies were obtained from patients of department of dermatology over a period of two years from 2017 to 2019. Among them Lepromatous leprosy were 43 cases, Tuberculoid leprosy were 23 cases, Borderline lepromatous leprosy were 09 cases, Borderline tuberculoid leprosy were 03 cases, histoid leprosy were 01 case and ENL were 01 case. With an age range of 6 - 85 years, majority were in 31-40 years of age group, with male to female ratio of 2.47:1. LL was the most common type of leprosy (53.75%).

CONCLUSIONS

Accurate diagnosis of leprosy purely on clinical grounds is extremely difficult. Hence, there can be false positive and false negative diagnosis. Since histopathology is confirmatory, with application of Fite-Faraco and MRAFB staining it can also evaluate the bacterial load. Hence in all suspected cases of leprosy, histopathology along with Fite-Faraco and MRAFB staining should compulsorily be done.

KEY WORDS

Acid Fast Bacilli, Bacterial Index, Fite-Faraco Stain, MRAFB Staining, Ridley-Jopling Classification

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