Clinicopathological Profile of Ca Stomach and Comparison of Preoperative Findings with Peroperative and Histopathological Findings.

Corresponding Author:
Dr. Arindam Das,
#18A, Santosh Roy Road,
Barisha, Kolkata-700008,
West Bengal, India.
E-mail: dasarindam1988@gmail.com

ABSTRACT

Gastric cancer has been one of the leading causes of cancer-related mortality over the past century. Today it is the 4^th most common cancer in the world. Surgery remains the only major curative option. Majority of these cancers are found to be unresectable on laparotomy. It is also frequently seen that patients with a preoperatively resectable cancer as per a staging CT-Scan of the abdomen are found to have unresectable disease on laparotomy. In this study, we are trying to assess the clinico-pathological profile of gastric cancer and tally the preoperative radiological findings with the peroperative and final histopathological findings.

METHODS

It is a short-term prospective, observational study. 50 patients with gastric cancer permitted surgical intervention were prepared, operated, followed-up and preoperative, peroperative and final histopathological findings were tallied.

RESULTS

50 patients with gastric cancer were studied. The maximum age was 76 years and minimum age was 23 years with a mean age of 49.12 years with a standard deviation of 13.9776. Peak incidence was found in the age group of 41-60 years. 54% of the patients were male and 46% were female. The most common symptom was anorexia (94%, z-value 8.8) followed by weight loss (86%, z-value 7.2). The most common sign was anaemia which was present in 80% of the patients (z-value 6.0). 64% of the patients had intestinal type while 36% had diffuse type of gastric cancer. Patients with diffuse type were <50 years of age. Diffuse type was more common in females while intestinal type was more common in males. The accuracy of T, N, M staging on preoperative CT-Scan tallied with peroperative findings is 44%, 38% and 72% respectively. 44% of the patients underwent a palliative surgical procedure, of which 90.9% had poorly-differentiated and 9.1% had moderately-differentiated cancer.

CONCLUSIONS

Preoperative CT-Scan may not be a very accurate staging investigation for gastric cancer. It is poorly-differentiated cancers (both adenocarcinoma and signet-ring cell carcinoma) which have a greater possibility of being inaccurately staged by a preoperative CT-Scan.

KEY WORDS

Gastric Cancer, Clinicopathological Profile, Preoperative Finding, Peroperative Findings