AN OVERVIEW OF GUILLAIN BARRE SYNDROME WITH REFERENCE TO CLINICAL FEATURES AND PROGNOSTIC OUTCOME IN PATIENTS ATTENDING A TERTIARY CARE HOSPITAL.

Corresponding Author:
Dr. Soumya Kanduri,
Flat No. 402, 39-22-11/2,
Sri Durga Residency, Kalinganagar,
Madhavadhara, Visakhapatnam-530007,
Andhra Pradesh, India.
E-mail: ksoumya1991@gmail.com

ABSTRACT

BACKGROUND

Guillain Barre Syndrome (GBS) is the most common cause of acute or subacute generalized paralysis in practice. Proper understanding of pathology, clinical presentation, appropriate investigations and interventions when needed may save these patients from mortality and severe morbidity. King George Hospital located in Visakhapatnam predominantly covers most of the population of North Coastal Andhra Pradesh, Odisha. It offers medical management to people of different age groups, races and different socio-economic status. Hence it is ideal to conduct a study in this institution.

Aims and Objectives- To evaluate the clinical features and assess the prognostic outcome in patients with Guillain Barre Syndrome.

MATERIALS AND METHODS

After taking prior consent, 40 patients of Guillain Barre Syndrome were studied from January 2016 to January 2017. Their clinical features, electrodiagnosis, treatment outcomes and prognosis were assessed.

RESULTS

18 patients had AIDP, 16 had AMAN, 12 had AMSAN, and 2 presented with the Miller Fischer variant. 38 patients received Intravenous Immunoglobulin (IVIG). 2 of them were given only Methyl Prednisolone. 5 patients went into respiratory failure despite being given IVIG and had to be given ventilator support. Patients with AIDP and AMAN showed recovery from Grade 5 to Grade 2. 2 patients with AMSAN variant had residual disability at the time of discharge. 12 patients had autonomic disturbance but recovered fully. There was no mortality among the study subjects during the period of study.

CONCLUSION

We can conclude from our study that Guillain Barre Syndrome is a treatable neurological condition with varying patterns of recovery. Intravenous immunoglobulin forms the mainstay of pharmacological treatment with recovery being shown in invariably all the patients who have received IVIG.

KEY WORDS

Guillain Barre Syndrome, Clinical Features, Prognosis.