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2016 Month : August Volume : 5 Issue : 67

ADVANTAGE OF CORE NEEDLE BIOPSY OVER FINE NEEDLE ASPIRATION CYTOLOGY IN PALPABLE BREAST LUMPS..

Guddi Rani Singh1, Manoj Kumar Rai2, Reecha Singh3, Bipin Kumar4, Vijayanand Choudhary5, Ajit Kumar6, Suryajit Kumar Singh7

Corresponding Author:
Dr. Reecha Singh,
E2/2 Quarter No.
Indira Gandhi Institute of Medical Sciences,
Patna-14.
E-mail: sreecha@ymail.com

ABSTRACT

OBJECTIVE

To study the advantage of Core Needle Biopsy (CNB) over Fine Needle Aspiration Cytology (FNAC) in palpable breast lumps by comparing the diagnostic accuracy in terms of sensitivity, specificity, positive and negative predictive values considering the histopathological diagnosis of incised or excised specimen as the gold standard.

METHODS

A prospective study of 100 female patients with palpable breast lump was conducted in the Department of Pathology of a tertiary care teaching hospital of Northern part of India. All the patients were randomly selected, irrespective of their age, religion, marital status, occupation or social status for FNAC following a thorough clinical check-up. During the study period, 54 patients were selected for core needle biopsy on the basis of insufficient FNAC material for making definitive diagnosis and for sub-typing the tumours. All core biopsy samples were subjected for histopathological examination. The diagnostic findings were compared with the histopathological findings of the lumpectomy or mastectomy specimen and with those of FNAC findings for each and every patient.

RESULTS

The sensitivity of FNAC and CNB was 96.29% and the specificity for malignant lesions was 100%. The positive predictive value was 100% and the negative predictive value was 95.12%.

CONCLUSION

There is no significant difference in the diagnostic accuracy between core needle biopsy and FNAC.

KEYWORDS

Core Needle Biopsy, Fine Needle Aspiration Cytology, Palpable Breast Lump.

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